Low forms of cyclin E reduce breast cancer drug’s effectiveness

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Overexpression of low-molecular-weight (LMW-E) forms of the protein cyclin E renders the aromatase inhibitor letrozole ineffective among women with estrogen-receptor-positive (ER+) breast cancers, researchers from The University of Texas M. D. Anderson Cancer Center report in Clinical Cancer Research .

http://www.bionity.com/news/e/113234/?WT.mc_id=ca0068

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